The bacterium's ability to persist inside host macrophages makes it difficult to treat, often requiring long-term combination antibiotic therapy.
In humans, it can cause a debilitating, chronic illness characterized by undulant fever, joint pain, and fatigue. abortus
In its primary host, cattle, B. abortus typically localizes in the reproductive tract. The hallmark clinical signs of infection include: The bacterium's ability to persist inside host macrophages
Even with treatment, relapse occurs in 5–15% of cases due to the presence of "persister" cells that remain metabolically active within protective intracellular niches. Current Control and Prevention Strategies it can cause a debilitating
Contagious abortion, often occurring in the last trimester of pregnancy, is the most common sign.