As cells pass a laser beam, the machine reads their size (forward scatter) and internal complexity (side scatter).
Morphology can suggest a lineage, but it cannot always prove it. Two cells might look identical but behave like total strangers. The Molecular Fingerprint (Flow Cytometry) Flow Cytometry in Neoplastic Hematology Morphol...
This is for informational purposes only. For medical advice or diagnosis, consult a professional. AI responses may include mistakes. Learn more As cells pass a laser beam, the machine
The true power lies in the overlap. A pathologist might see "monomorphous medium-sized blasts" (Morphology) and use Flow Cytometry to confirm they are actually "CD10+ B-lymphoblasts." The Molecular Fingerprint (Flow Cytometry) This is for
The microscopic world of hematology is often a battle between what we see and what is actually there. In the diagnosis of neoplastic diseases, the "story" is one of collaboration between traditional morphology and the high-tech precision of flow cytometry. The Visual Clues (Morphology)
It detects "CD markers" (Clusters of Differentiation). CD34: Signals a primitive, immature cell. CD19/CD20: Confirms a B-cell lineage. CD13/CD33: Points toward myeloid involvement. The Synthesis: A Final Diagnosis