How Effective Is The Flu - Vaccine?

30%–42% effective depending on age and setting. Influenza B: 45%–71% effective. Why Effectiveness Varies

The primary reason for lower effectiveness this season is a with the dominant H3N2 "subclade K" strain. This mutated version emerged after the 2025–26 vaccine composition was already finalized. Other factors include: CDC Seasonal Flu Vaccine Effectiveness Studies How Effective is the Flu Vaccine?

For the current , the vaccine is estimated to be 36% effective overall at preventing medically attended flu illness. While this is lower than the typical 40–60% range, it still significantly reduces the risk of severe complications, hospitalizations, and deaths. Key Effectiveness Data (2025–26 Season) Overall Effectiveness: 36% (interim estimate). By Age Group: 30%–42% effective depending on age and setting