Kbmp4 «EXCLUSIVE»
High KBMP4 scores often signal that standard R-CHOP therapy may not be enough, potentially leading to more intensive consolidative strategies or clinical trials.
The model is a clinical scoring system used to predict the survival and prognosis of patients with de novo Diffuse Large B-cell Lymphoma (DLBCL) . High KBMP4 scores often signal that standard R-CHOP
High proliferation index (Ki67 ≥ 70%) on immunohistochemistry. B (Bulky): Physical presence of a tumor mass ≥ 7.5 cm. B (Bulky): Physical presence of a tumor mass ≥ 7
While the International Prognostic Index (IPI) is the standard, KBMP4 provides a more granular look at aggressive "Double-Hit" or "Double-Expression" lymphomas. The model categorizes patients into three risk groups
If you are looking for or comparisons to other models like the IPI or NCCN-IPI , I can provide those details.
The model categorizes patients into three risk groups based on how many of these four parameters they meet: Risk Subgroup Criteria (Parameters met) Progression-Free Survival (PFS) Overall Survival (OS) 0 parameters Intermediate 1 or 2 parameters High-Risk 3 or more parameters