" Changes " is the title of the premiere episode of Season 2 for the Spanish medical drama series (original title: Respira ), which aired on November 2, 2025 .
: Begins a journey toward recovery from addiction under the care of Dr. Neus. [S2E1] Changes
: The chaos begins with Pilar ordering Biel to perform a high-stakes operation on a bleeding Jesica. While Jesica initially appears to recover, she later experiences severe hallucinations—a side effect of toxins reaching her brain—and tragically cuts herself open in a state of distress. " Changes " is the title of the
: Faces professional confusion as he is asked to juggle a double residency in oncology and general surgery while dealing with Jesica's erratic behavior. which aired on November 2