The protein utilizes several C2 domains (C2A-C2F) to bind Ca 2+raised to the 2 plus power and lipids, as shown in the protein structure below. 2. C2 Domains: Function & Interactions
Binding Sites: High-resolution structures revealed that multiple Ca 2+raised to the 2 plus power tm,cc,jp
Otoferlin engages the target membrane specifically through a large interface involving the N-terminal C2B and C-terminal C2F-C2G domains . Ca 2+raised to the 2 plus power The protein utilizes several C2 domains (C2A-C2F) to