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In Season 5, Episode 16, titled " The Vacation Solution ," Sheldon Cooper is forced by the university to take a mandatory vacation. Unwilling to stop working, he decides to "vacation" in Amy's neurobiology lab, where he quickly finds himself struggling to follow her orders. Episode Details Original Air Date: February 9, 2012 Director: Mark Cendrowski

After rejecting ideas like Hawaii (too volcanic) and Florida (seagulls stole his hot dog), Sheldon attempts to work in Amy's lab. His arrogance leads to conflict when Amy assigns him menial tasks like cleaning beakers. Watch www xrysoi se The Big Bang Theory - S05E16

Bernadette insists that Howard sign a pre-nuptial agreement before their wedding. This causes tension as Howard deals with his own feelings about the request and his father-in-law's involvement. In Season 5, Episode 16, titled " The